The Continuum of Health Risk Assessments

The Continuum of Health Risk AssessmentsThe Continuum of Health Risk Assessments. Edited by Michael G. Tyshenko, ISBN 980-953-307-582-7, Hard cover, 194 pages, Publisher: InTech, Published: May 16, 2012 under CC BY 3.0 license, in subject Public Health. DOI: 10.5772/2689


This book presents a collection of health risk assessments for known and emerging hazards that span a continuum. Case studies for existing health risks include psychoactive drug usage in delivery truck drivers and using look-back risk assessment for accidental syringe re-use in healthcare settings. Case studies for emerging risks include precautionary actions to safeguard blood supplies; nanoparticle deposition in the lung; and the epistemic issues surrounding genetically modified organism risk assessments. The final section of the book deals with advancing health risk assessment analyses through a post-genomics lens and provides case studies on personalized genomics, new data analyses and improving in silico models for risk assessment. These case studies provide much insight into the ongoing evolution of health risk assessments.

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Preface IX 

Part 1
Typical Health Risk Assessment Case Studies for Novel Risks


Chapter 1
The Risk of Blood-Borne Viral Infection due to Syringe Re-Use
Tamer Oraby, Susie Elsaadany, Robert Gervais, Mustafa Al-Zoughool, Michael G. Tyshenko, Lynn Johnston, Mel Krajden, Dick Zoutman, Jun Wu and Daniel Krewski


Chapter 2
Professional Drivers and Psychoactive Substances Consumption: First Results from Medical Surveillance at the Workplace in Italy
Gian Luca Rosso, Mauro Feola, Maria Paola Rubinetto, Nicola Petti and Lorenzo Rubinetto


Part 2
Health Risk Assessment Case Studies for Emerging Risks


Chapter 3
Xenotropic Murine Leukemia Virus-Related Virus as a Case Study: Using a Precautionary Risk Management Approachfor Emerging Blood-Borne Pathogens in Canada
Michael G. Tyshenko, Susie ElSaadany, Tamer Oraby, Marian Laderoute, Jun Wu, Willy Aspinall, Daniel Krewski and Peter R. Ganz


Chapter 4
Ultrafine and Fine Aerosol Deposition in the Nasal Airways of a 9-Month-Old Girl, a 5-Year-Old Boyand a 53-Year-Old Male
Jinxiang Xi, JongWon Kim and Xiuhua A. Si


Chapter 5
Safety, Security and Quality: Lessons from GMO Risk Assessments
Alice Benessia and Giuseppe Barbiero


Part 3
Improving Future Risk Assessment Analyses


Chapter 6
Breast Cancer Prognostication and Risk Prediction in the Post-Genomic Era
Xi Zhao, Ole Christian Lingjærde and Anne-Lise Børresen-Dale


Chapter 7
Physics of Open Systems: A New Approach to Use Genomics Data in Risk Assessment
Viacheslav Ageev, Boris Fomin, Oleg Fomin, Tamara Kachanova, Chao Chen, Maria Spassova and Leonid Kopylev


Chapter 8
New Models for the In Vitro Study of Liver Toxicity: 3D Culture Systems and the Role of Bioreactors
Giovanna Mazzoleni and Nathalie Steimberg